Meet CeDawn

Alzheimer's, measured against normal.

See what matters. Earlier. Cerebramha.

CeDawn · Report CD-2025-0419
Sample case CBX-0419 · F · 74 yScan 2025-01-15
Coronal MRI slice at the level of the hippocampusRLCOR · y −18.6 mmT1 · 1 mm hippocampus ventricles
Regionml0100Pctl
Hippocampus2.746th
Entorhinal1.428th
Amygdala1.2819th
Post. cingulate2.3022nd
Fusiform7.6034th
Precuneus7.9038th

normal range for age and sexthis measurement

36-month MCI to AD

58%High

Model: imaging + clinical. Inputs: MMSE 24 · APOE4 ε4 ×1. Drivers: hippocampus, entorhinal cortex, ventricles.

The problem

The window that keeps closing

Alzheimer's is most treatable early, and the newest therapies only work at that stage. The signal is already in the MRI, in shrinkage too subtle to quantify by eye.

By eyeUnmeasured
Coronal MRI slice at the level of the hippocampusRLCOR · y −18.6 mmT1 · 1 mm

Hippocampus. Smaller than it should be? Hard to say.

Read visually, slice by slice. No number.

CeDawnMeasured
Coronal MRI slice at the level of the hippocampusRLCOR · y −18.6 mmT1 · 1 mm hippocampus

Hippocampus, 2.74 ml. Normal: 3.40 to 3.92.

6th percentile, z -1.55, for her age and sex.

Hippocampus

Measured against normal

6th pctl

2.74 mlnormal 3.403.92

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How it works

What CeDawn does

Three steps from a standard MRI to a one-page report.

Coronal MRI slice at the level of the hippocampus

1Measures the regions that matter

The regions affected earliest are measured automatically from a standard MRI. No manual tracing.

Region0100Pctl
Hippocampus6th
Entorhinal8th
Amygdala19th
Post. cingulate22nd

normal range for age and sexthis measurement

2Compares against normal

Each region is placed against a reference population matched for age and sex: the measurement, the normal range, and the percentile.

36-month estimate

58%High

ScanAgeSexMMSE 24APOE4 ×1+ CSF refines

3Looks forward

A 36-month estimate of progression from MCI to Alzheimer's, from the scan, age, and sex. Cognitive or genetic data refine it.

Why it's different

Not a black box

A score with no reasoning is unusable to a clinician. CeDawn shows the measurement, the normal range, and the regions behind the estimate.

Coronal MRI slice at the level of the hippocampusRLCOR · y −18.6 mmT1 · 1 mm hippocampus ventricles
Hippocampus2.74 ml
Entorhinal1.42 ml
Amygdala1.28 ml
Post. cingulate2.30 ml

Where we are

Where we are

CeDawn is a research platform. It runs end to end today, and we're validating it with clinical and research partners. It is not a cleared medical device and does not replace clinical judgment. We're building the evidence base for clearance, with research groups like yours.

Runs end to end todayValidating with clinical partnersNot a cleared medical device

Building the validation

Building the validation, together

Run CeDawn on your cohorts. You get a novel quantitative measure and progression estimate for your own work, with co-authorship on what comes out of it. Collaborators, not vendors.

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Research groups · co-authorship